Serago C F, Houdek P V, Pisciotta V, Schwade J G, Abitbol A A, Lewin A A, Poole D O, Marcial-Vega V
Cancer Treatment Center, Baptist Hospital of Miami, Florida 33176.
Med Phys. 1991 Nov-Dec;18(6):1266-70. doi: 10.1118/1.596602.
Dosimetry calculations for iridium-192 sources generally assume that a sufficient medium surrounds both the iridium source(s) and the point of calculation so that full scattering conditions exist. In several clinical applications the iridium sources may be anatomically located so that the full scattering requirement is not satisfied. To assess the magnitude of this problem, relative measurements were made with a small ionization chamber in phantoms near air and lung-equivalent interfaces. Dose reduction caused by decreasing the volume of scattering material near these interfaces was then evaluated for a few clinical applications. The results show that reductions on the order of 8% may be expected at the interface with minimal dose reduction within the volume of the implant itself. In addition, the results indicate the verification of source strength of iridium sources in phantom require phantom dimensions determined by the source-chamber separation distance.
铱-192源的剂量学计算通常假定在铱源和计算点周围有足够的介质,以便存在完全散射条件。在一些临床应用中,铱源的解剖位置可能导致无法满足完全散射的要求。为了评估这个问题的严重程度,在靠近空气和肺等效界面的体模中使用小型电离室进行了相对测量。然后针对一些临床应用评估了这些界面附近散射材料体积减小所导致的剂量降低情况。结果表明,在界面处可能预期有8%左右的剂量降低,而植入物自身体积内的剂量降低最小。此外,结果表明在体模中验证铱源的源强需要由源-电离室分离距离确定的体模尺寸。