Zhong Zhen-guo, Zhang Feng-fen, Zhang Wen-yan, Cui Jian-guo
Guangxi College of Traditional Chinese Medicine, Nanning 530001, China.
Zhong Yao Cai. 2007 Jan;30(1):60-3.
To observe the effects of extracts from root of Livistona chinensis on the growth inhibition in seven carcinoma cell lines.
The growth inhibition was analyzed by MTT, cell colony and cell growth curve measuremen technique in the stomach carcinoma SGC7901, Lymphocytic leukemia L1210, Lymphoid neoplasm P388D1, tumor of cervix uteri Hela, hepar carcinoma hele 7404, melanoma B16 and mouse neuroblastomax rat glioma hybrid NG108-15 cells lines.
The growth of all tumor cells were inhibited by ethyl acetate of alcohol extract from roots of Livistona chinensis. The growth of all tumor cells were not affected by low dose extracts (0.5 microg/ml). The growth of all tumor cells were obviously inhibited by higher dose extracts (5.0 microg/ml). The growth of all tumor cells were inhibited in growth curve measurement.
The results show that ethyl acetate of alcohol extracts from roots Livistona chinensis possesses the role of antitumor in cell culture.
观察蒲葵根提取物对七种癌细胞系生长抑制的影响。
采用MTT法、细胞集落法及细胞生长曲线测定技术，分析蒲葵根提取物对胃癌SGC7901、淋巴细胞白血病L1210、淋巴瘤P388D1、子宫颈癌Hela、肝癌Hele 7404、黑色素瘤B16及小鼠神经母细胞瘤大鼠胶质瘤杂交瘤NG108 - 15细胞系的生长抑制作用。
蒲葵根乙醇提取物的乙酸乙酯部位对所有肿瘤细胞的生长均有抑制作用。低剂量提取物（0.5微克/毫升）对所有肿瘤细胞的生长无影响。高剂量提取物（5.0微克/毫升）对所有肿瘤细胞的生长有明显抑制作用。在生长曲线测定中，所有肿瘤细胞的生长均受到抑制。
结果表明，蒲葵根乙醇提取物的乙酸乙酯部位在细胞培养中具有抗肿瘤作用。
