Chu Ming, Chu Zheng-yun, Wang Dan-dan
Department of Immunology, School of Basic Medicine, Peking University, Beijing 100083, China.
Zhong Yao Cai. 2007 Jan;30(1):63-5.
To study the extract of compound Radix Scutellariae on inhibiting the mRNA replication and inducing the INF expression of influenza virus in mice's vivo.
Influenza virus infected mice pneumono-adaption stock A/FM/1/47 (H1N1) evoked mice pneumonia taken as animal model. RT-PCR was adopted to measure the content of influenza virus's mRNA and INF in mice to study the effect of the extract on mRNA replication and IFN expression.
The extract of compound Radix Scutellariae could inhibit influenza virus' s mRNA replication (P < 0.01) and induce interferon expression in mice (P > 0.05).
The extract of compound Radix Scutellariae can induce interferon and inhibit influenza virus replication in mice.
