Liu Xiao-ping, Wang Ying, Yan Lie-xiang, Shi Bin
College of Chemical Engineering, Wuhan University of Technology, Wuhan 430070, China.
Zhong Yao Cai. 2007 Jan;30(1):82-5.
To study the technique of preparation and optimization of magnetic chitosan microspheres.
Magnetic fluid was produced by co-precipitation method and magnetic chitosan microspheres were produced using a convenient method of ionic gelation. A global optimization algorithm was used to optimize the parameters.
The formulated magenetic fluid and microspheres were characterized size and the size distribution. The average particle size of magnetic fluid and matrine-loaded chitosan magnetic microspheres were found to be 152.2 nm and 682.4 nm.
Global optimization algorithm is an efficient method to optimize the parameters.
