一种来自卡布番荔枝（野牡丹科）的异常的C6-C6”连接的黄酮类化合物。

An unusual C6-C6" linked flavonoid from Miconia cabucu (Melastomataceae).

作者信息

Rodrigues Juliana, Rinaldo Daniel, dos Santos Lourdes Campaner, Vilegas Wagner

机构信息

Instituto de Química, Universidade Estadual Paulista, UNESP, C.P. 355, 14801-97, Araraquara, São Paulo, Brazil.

出版信息

Phytochemistry. 2007 Jul;68(13):1781-4. doi: 10.1016/j.phytochem.2007.04.020. Epub 2007 May 30.

DOI:10.1016/j.phytochem.2007.04.020

PMID:17540417

Abstract

Chromatographic fractionation of the methanolic extract from the leaves of Miconia cabucu Hoehne (Melastomataceae) afforded the first example of a C(6)-C(6") linked flavone dimer, 5-hydroxy-4',7-dimethoxyflavone-(6-C-6'')-5''-hydroxy-3''',4''',7''-trimethoxyflavone as well as the known compounds, quercetin-3-O-alpha-l-rhamnopyranosyl-(2-->1)-O-beta-D-xylopyranoside, quercetin-3-O-alpha-l-rhamnopyranoside, myricetin-3-O-alpha-l-rhamnopyranoside, quercetin-3-O-beta-D-glucopyranoside, kaempferol-3-O-beta-D-(6''-coumaroyl)-glucopyranoside and gallic acid. Their chemical identities were established by application of NMR spectroscopic methods including 2D-NMR, as well as UV and ESI-MS analyses.

摘要

对巴西野牡丹（野牡丹科）叶片的甲醇提取物进行色谱分离，得到了首例C(6)-C(6")连接的黄酮二聚体，即5-羟基-4',7-二甲氧基黄酮-(6-C-6'')-5''-羟基-3''',4''',7''-三甲氧基黄酮，以及已知化合物槲皮素-3-O-α-L-鼠李糖基-(2→1)-O-β-D-木糖苷、槲皮素-3-O-α-L-鼠李糖苷、杨梅素-3-O-α-L-鼠李糖苷、槲皮素-3-O-β-D-葡萄糖苷、山柰酚-3-O-β-D-(6''-香豆酰基)-葡萄糖苷和没食子酸。通过应用包括二维核磁共振在内的核磁共振光谱方法以及紫外和电喷雾电离质谱分析确定了它们的化学结构。