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止泻木(Holarrhena antidysenterica (L.) WALL.)中的甾体生物碱

Steroidal alkaloids from Holarrhena antidysenterica (L.) WALL.

作者信息

Kumar Neeraj, Singh Bikram, Bhandari Pamita, Gupta Ajai Prakash, Kaul Vijay Kumar

机构信息

Natural Plant Products Division, Institute of Himalayan Bioresource Technology.

出版信息

Chem Pharm Bull (Tokyo). 2007 Jun;55(6):912-4. doi: 10.1248/cpb.55.912.

DOI:10.1248/cpb.55.912
PMID:17541193
Abstract

Chemical investigations on the stem bark of Holarrhena antidysenterica resulted in the isolation of a new steroidal alkaloid designated as holadysenterine (1), together with three known steroidal alkaloids, conessine (2), isoconessimine (3) and kurchessine (4). Their structures were elucidated on the basis of 1D- and 2D-NMR techniques and high-resolution mass spectrometry.

摘要

对止泻木茎皮进行化学研究,结果分离出一种新的甾体生物碱,命名为止泻木碱(1),以及三种已知的甾体生物碱,锥丝碱(2)、异锥丝次碱(3)和库契辛(4)。基于一维和二维核磁共振技术以及高分辨率质谱对它们的结构进行了阐明。

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