Malemba J J, Mbuyi-Muamba J M
Department of Internal Medicine, Kinshasa University Hospital, Post Box 123, Kinshasa XI, Democratic Republic of Congo.
Clin Rheumatol. 2008 Jan;27(1):47-54. doi: 10.1007/s10067-007-0650-x. Epub 2007 Jun 2.
The aim of the present retrospective and hospital-based study was to describe epidemiological and clinical features of rheumatic diseases in patients attending the University Hospital of Kinshasa (UHK). Rheumatic complaint was a reason for consultation in 12.1% of outpatients attending the Department of Internal Medicine of the UHK. Osteoarthritis was the most common rheumatic disease (59.2%), followed by soft tissue rheumatism (16.1%), gout (9.3%), and spondylarthropathies (7.5%). The cumulative frequency of autoimmune diseases (rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, dermatomyositis, and mixed connective tissues disease) and the frequency of osteoporosis were 5.2 and 2.7%, respectively. Lumbar spine was the part of the skeleton mostly affected by osteoarthritis. Pathological fractures in osteoporosis, subcutaneous nodules, rheumatoid factor, and erosive bone lesions in rheumatoid arthritis were rarely found. Compared to the previous studies performed in the same hospital, our results disclose a threefold increase of rheumatic outpatients. The paucity of erosive arthritis and extra-articular manifestations suggest the less severity of rheumatoid arthritis in our patients. Likewise, the absence of femoral and wrist osteoporotic fractures and the scarcity of advanced vertebral crush fractures suggest the mildness of osteoporosis.
本项基于医院的回顾性研究旨在描述金沙萨大学医院(UHK)就诊患者的风湿性疾病的流行病学和临床特征。在UHK内科门诊患者中,12.1%的患者因风湿性疾病主诉前来就诊。骨关节炎是最常见的风湿性疾病(59.2%),其次是软组织风湿病(16.1%)、痛风(9.3%)和脊柱关节病(7.5%)。自身免疫性疾病(类风湿关节炎、系统性红斑狼疮、系统性硬化症、皮肌炎和混合性结缔组织病)的累积发生率和骨质疏松症的发生率分别为5.2%和2.7%。腰椎是骨关节炎最常累及的骨骼部位。骨质疏松症中的病理性骨折、皮下结节、类风湿因子以及类风湿关节炎中的侵蚀性骨病变均很少见。与此前在同一医院开展的研究相比,我们的结果显示风湿性门诊患者增加了两倍。侵蚀性关节炎和关节外表现较少表明我们的患者中类风湿关节炎的严重程度较低。同样,股骨和腕部骨质疏松性骨折的缺失以及严重椎体压缩性骨折的罕见表明骨质疏松症较轻。