Dai Sheng-Ming, Han Xing-Hai, Zhao Dong-Bao, Shi Ye-Qing, Liu Yu, Meng Ji-Ming
Department of Rheumatology and Immunology, Changhai Hospital, Second Military Medical University, 174 Changhai Road, Shanghai 200 433, China.
J Rheumatol. 2003 Oct;30(10):2245-51.
To carry out a cross-sectional survey on prevalence of musculoskeletal symptoms, rheumatoid arthritis (RA), ankylosing spondylitis (AS), and gout.
In Shanghai, 4 communities comprising 7603 inhabitants over 15 years of age in an urban population were randomly selected from 13 communities. Interviews were conducted from September 1997 to March 1998 by trained physicians using the COPCORD Core Questionnaire. Physical and radiographic examinations and serologic tests were carried out when required to classify categories of rheumatic diseases. The diagnoses of RA, systemic lupus erythematosus (SLE), and gout were based on American Rheumatism Association criteria. The diagnosis of AS strictly followed the modified New York criteria of 1984. Crude prevalence rates were standardized according to a standard Chinese population for age and sex structure.
A total of 6584 adults (3394 women, 3190 men) were interviewed, and response rate was 86.6%. The age and sex standardized prevalence rate of rheumatic symptoms at any site amounted to 13.3% (95% CI 12.5-14.1%). Symptoms occurred more frequently in the following sites: knee 7.0% (95% CI 6.4-7.6%), lower back 5.6% (95% CI 5.0-6.2%), shoulder 4.7% (95% CI 4.2-5.2%), and neck 2.4% (95% CI 2.0-2.8%). Women complained of rheumatic symptoms more frequently than men. The standardized rates of RA, AS, gout, symptomatic knee osteoarthritis, and soft tissue rheumatism were 0.28% (95% CI 0.15-0.41%), 0.11% (95% CI 0.03-0.19%), 0.22% (95% CI 0.11-0.33%), 4.1% (95% CI 3.6-4.6%), and 3.4% (95% CI 3.0-3.8%), respectively. Two cases of SLE, one case of dermatomyositis, and one case of systemic sclerosis were found.
Compared with rates in European and Western countries the prevalence rates of RA, AS, and gout are low in Shanghai, China, although the prevalence rates of rheumatic symptoms are high.
开展一项关于肌肉骨骼症状、类风湿关节炎（RA）、强直性脊柱炎（AS）和痛风患病率的横断面调查。
在上海，从13个社区中随机选取4个社区，涵盖7603名15岁以上的城市居民。1997年9月至1998年3月，由经过培训的医生使用COPCORD核心问卷进行访谈。根据需要进行体格检查、影像学检查和血清学检测，以对风湿性疾病进行分类。RA、系统性红斑狼疮（SLE）和痛风的诊断依据美国风湿病协会标准。AS的诊断严格遵循1984年修订的纽约标准。根据中国标准人群的年龄和性别结构对粗患病率进行标准化。
共访谈了6584名成年人（3394名女性，3190名男性），应答率为86.6%。任何部位风湿症状的年龄和性别标准化患病率为13.3%（95%可信区间12.5 - 14.1%）。症状在以下部位更频繁出现：膝关节7.0%（95%可信区间6.4 - 7.6%），下背部5.6%（95%可信区间5.0 - 6.2%），肩部4.7%（95%可信区间4.2 - 5.2%），颈部2.4%（95%可信区间2.0 - 2.8%）。女性比男性更频繁地抱怨有风湿症状。RA、AS、痛风、症状性膝关节骨关节炎和软组织风湿病的标准化患病率分别为0.28%（95%可信区间0.15 - 0.41%）、0.11%（95%可信区间0.03 - 0.19%）、0.22%（95%可信区间0.11 - 0.33%）、4.1%（95%可信区间3.6 - 4.6%）和3.4%（95%可信区间3.0 - 3.8%）。发现2例SLE、1例皮肌炎和1例系统性硬化症。
与欧洲和西方国家的患病率相比，中国上海RA、AS和痛风的患病率较低，尽管风湿症状的患病率较高。
