Mårdh P A, Colleen S
Scand J Urol Nephrol. 1975;9(1):8-16. doi: 10.3109/00365597509139906.
Seventy-nine patients with symptoms of nonacute prostatitis and 20 healthy volunteers were examined for uro-genital tract infection with bacteria, mycoplasmas, fungi, trichomonads and viruses. No differences in the results of the bacterial cultures were found between the patients and the controls. In only a few cases were established urinary tract pathogens found, but in no instance were these findings reproducible in later specimens. The cultures of the expressed prostatic fluids and the samples of semen gave no information of the occurrence of bacteria over and above that obtainable from examination of the urethral specimens. Significant bacteriuria was not found in any of the patients. Though Neisseria gonorrhoeae could not be isolated from any of the subjects, immunofluorescent studies revealed such organisms in seminal fluid in 8% of the patients. Nine of the patients had 1 to 3 years been considered successfully treated for gonorrhoea. Five of these nine patients were still found to harbour gonococci, as judged from the immunofluorescent studies. Corynebacterium vaginale was recovered in an equally low frequency (5%) from the patients and the volunteers. There was no significant difference in the incidence of T-mycoplasmas between the patients (46%) and the controls (35%), while Mycoplasma hominis was only found in the patients (10%). Trichomonas vaginalis could not be detected in wet smears of expressed prostatic fluid in any of the subjects, but could be cultured from one such specimen. Metacycline treatment (performed according the double blind cross-over technique) was studied for effects on the bacterial flora. In about 10% of the patients, an earlier not observed relative dominance of gram-negative rods was found on the cultures made after the therapy. Candida albicans was only isolated from the patients. It was found more often after (24%) than before the (15%) treatment. Complement-fixing antibodies to N. gonorrhoeae, cytomegalovirus and Chlamydia were found in 10, 19, and 33% of the patients, respectively. The corresponding figures for the healthy males were 0, 20 and 5%.
对79例非急性前列腺炎症状患者和20名健康志愿者进行了泌尿生殖道细菌、支原体、真菌、滴虫和病毒感染检查。患者与对照组的细菌培养结果无差异。仅在少数病例中发现了确诊的尿路病原体，但这些结果在后来的标本中均无法重现。前列腺液和精液样本的培养，除了从尿道标本检查中可获得的信息外，未提供有关细菌存在情况的更多信息。所有患者均未发现显著菌尿。虽然未从任何受试者中分离出淋病奈瑟菌，但免疫荧光研究显示8%的患者精液中有此类病原体。其中9名患者曾被认为淋病已成功治愈1至3年。根据免疫荧光研究判断，这9名患者中有5名仍携带淋球菌。阴道棒状杆菌在患者和志愿者中的检出频率同样较低（5%）。患者（46%）和对照组（35%）之间T-支原体的发生率无显著差异，而人型支原体仅在患者中发现（10%）。在任何受试者的前列腺液湿涂片中均未检测到阴道毛滴虫，但可从一份此类标本中培养出该病原体。研究了美满霉素治疗（根据双盲交叉技术进行）对细菌菌群的影响。在约10%的患者中，治疗后培养发现革兰氏阴性杆菌出现了此前未观察到的相对优势。白色念珠菌仅从患者中分离出。治疗后（24%）比治疗前（15%）更常发现。分别在10%、19%和33%的患者中发现了针对淋病奈瑟菌、巨细胞病毒和衣原体的补体结合抗体。健康男性的相应数字分别为0、20%和5%。
