Gater David R
Spinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC (652/128), 1201 Broad Rock Boulevard, Richmond, VA 23249, USA.
Phys Med Rehabil Clin N Am. 2007 May;18(2):333-51, vii. doi: 10.1016/j.pmr.2007.03.004.
America is in the midst of an obesity epidemic, and individuals who have spinal cord injury (SCI) are perhaps at greater risk than any other segment of the population. Recent changes in the way obesity has been defined have lulled SCI practitioners into a false sense of security about the health of their patients regarding the dangers of obesity and its sequelae. This article defines and uses a definition of obesity that is more relevant to persons who have SCI, reviews the physiology of adipose tissue, and discusses aspects of heredity and environment that contribute to obesity in SCI. The pathophysiology of obesity is discussed relative to health risks for persons who have SCI, particularly those contributing to cardiovascular disease. Prevalence of obesity and its comorbidities are discussed and management options reviewed.
美国正处于肥胖流行之中,脊髓损伤(SCI)患者可能比其他任何人群面临更大的风险。肥胖定义的近期变化使脊髓损伤从业者在患者肥胖及其后遗症的健康问题上产生了一种错误的安全感。本文定义并采用了一种与脊髓损伤患者更相关的肥胖定义,回顾了脂肪组织的生理学,并讨论了导致脊髓损伤患者肥胖的遗传和环境因素。文中讨论了肥胖的病理生理学与脊髓损伤患者的健康风险,特别是那些导致心血管疾病的风险。还讨论了肥胖及其合并症的患病率,并回顾了管理方案。