Okano Hideyuki, Kaneko Shinjiro, Okada Seiji, Iwanami Akio, Nakamura Masaya, Toyama Yoshiaki
Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
Neurochem Int. 2007 Jul-Sep;51(2-4):68-73. doi: 10.1016/j.neuint.2007.04.013. Epub 2007 May 1.
Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.
尽管长期以来人们一直认为受损的中枢神经系统在损伤后不会再生，但由于发育生物学和再生医学（包括干细胞生物学）的进展，基于再生的受损中枢神经系统（CNS）治疗方法出现了新的希望。在这篇综述中，我们总结了近期旨在开发基于再生的脊髓损伤治疗方法的研究，包括抗炎细胞因子治疗、神经干/前体细胞移植和轴突再生诱导。
