Vella M A, Sulke A N, Rodrigues C A, McNabb W R, Lewis R R
Department of Geriatrics and General Medicine, Guy's Hospital, London, UK.
Postgrad Med J. 1991 Aug;67(790):745-6. doi: 10.1136/pgmj.67.790.745.
Fifty elderly patients who had suffered cerebrovascular incidents from no obvious cause and 33 age-matched controls were investigated for the presence of a patent foramen ovale by contrast 2-dimensional echocardiography at rest and after the Valsalva manoeuvre. Right-to-left shunting was found in only one patient and in none of the controls. This finding is in contradistinction to young adult stroke patients in whom the prevalence of a haemodynamically significant patent foramina ovale is high. Paradoxical embolism is an uncommon cause of stroke in the elderly.
对50例无明显病因发生脑血管事件的老年患者和33例年龄匹配的对照者，通过静息状态及Valsalva动作后的对比二维超声心动图检查卵圆孔未闭情况。仅1例患者发现有右向左分流，而对照组均未发现。这一发现与年轻成年卒中患者不同，后者血流动力学上有意义的卵圆孔未闭患病率很高。反常栓塞在老年人卒中中是一种不常见的病因。
