Clucas Luisa, Doyle Lex W, Dawson Jennifer, Donath Susan, Davis Peter G
Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Australia.
Pediatrics. 2007 Jun;119(6):1056-60. doi: 10.1542/peds.2006-3099.
The objective of this study was to determine the rate of compliance with hospital guidelines for alarm limits for pulse oximetry in preterm infants on oxygen therapy.
All infants admitted to the nurseries at the Royal Women's Hospital, Melbourne, Australia, with gestational age <32 weeks or birth weight <1500 g between August 2005 and February 2006 were eligible for inclusion. Data on the alarm limits set for infants on oxygen therapy were collected prospectively. The target saturation range recommended in written hospital guidelines was 88% to 92%, with alarm limits set at 85% and 94%.
Data were prospectively collected for 144 subjects with mean (SD) gestational age 29.3 (2.4) weeks and birth weight 1226 (354) g; 1073 alarm limits were collected when infants were on oxygen. The lower alarm limit was set correctly 91.1% of the time. In contrast, the upper alarm limit was set correctly only 23.3% of the time: 76.5% of the time it was too high, and 23.8% of the time it was set at 100%. Infants with an upper alarm limit set correctly on a particular day had a significantly lower birth weight, gestational age, postmenstrual age, and postnatal age than infants who had the upper alarm limit set too high. Use of assisted ventilation, higher inspired oxygen concentrations, and more frequent changes in inspired oxygen concentration were all associated with improved odds of having an appropriately set upper alarm limit.
This study suggests that current guidelines regarding the upper pulse oximeter alarm limit for infants receiving oxygen might be commonly exceeded, although compliance might be better for infants at higher risk of adverse outcomes. However, there might be less variation from guidelines for the lower alarm limit.
本研究的目的是确定接受氧疗的早产儿脉搏血氧饱和度报警限的医院指南遵循率。
2005年8月至2006年2月期间入住澳大利亚墨尔本皇家妇女医院新生儿病房、胎龄<32周或出生体重<1500g的所有婴儿均符合纳入标准。前瞻性收集氧疗婴儿的报警限数据。医院书面指南推荐的目标饱和度范围为88%至92%,报警限设定为85%和94%。
前瞻性收集了144名受试者的数据,其平均(标准差)胎龄为29.3(2.4)周,出生体重为1226(354)g;婴儿吸氧时收集到1073个报警限。较低报警限的正确设置率为91.1%。相比之下,较高报警限的正确设置率仅为23.3%:76.5%的时间设置过高,23.8%的时间设置为100%。特定日期较高报警限设置正确的婴儿,其出生体重、胎龄、月经后年龄和出生后年龄显著低于较高报警限设置过高的婴儿。使用辅助通气、较高的吸入氧浓度以及更频繁地改变吸入氧浓度均与较高报警限设置适当的几率增加相关。
本研究表明,尽管对于不良结局风险较高的婴儿,指南遵循情况可能较好,但目前关于接受氧疗婴儿脉搏血氧饱和度较高报警限的指南可能经常被突破。然而,较低报警限与指南的差异可能较小。