Geffroy Y, Colin R, Testart J, Bourreille J, Ledouarec P, Paillot B, Joram F
Sem Hop. 1975 Mar 20;51(14):927-34.
Massive ascites is are complication, but not exceptional, in pancreatitis. In a series of ten personal cases and a review of one hundred cases in the world literature, the authors attempt to define the main pathological and clinical characteristics of this disease and the best treatment. Ascites may follow abdominal trauma, involving the pancreas, sometimes it occurs during known chronic pancreatitis, often it is the first sign of pancreatic disease, whether acute or chronic. High levels of pancreatic enzymes in the ascitic fluid are the main factor in diagnosis of pancreatic ascites. The mechanism of formation of the ascites is loss of pancreatic fluid into the peritoneal cavity owing to a breach in the pancreas, the presence of enzyme-rich fluid, causing secondarily "chemical" peritonitis. Paracentesis abdominis or drainage of the fluid during exploratory laparotomy, permits one to obtain in certain cases, a cure of the ascites, but surgical drainage by an anastomosis between the pancreatic cyst and the digestive tract (pancreatico-digestive anastomosis), has the advantage of ensuring treatment of the ascites and of the responsible pancreatic disease.
大量腹水是胰腺炎的一种并发症,但并非罕见。在作者的10例个人病例系列以及对世界文献中100例病例的回顾中,作者试图明确这种疾病的主要病理和临床特征以及最佳治疗方法。腹水可能继发于涉及胰腺的腹部创伤,有时发生在已知的慢性胰腺炎期间,通常它是胰腺疾病(无论是急性还是慢性)的首发症状。腹水中高水平的胰腺酶是诊断胰源性腹水的主要因素。腹水形成的机制是由于胰腺破裂,胰液漏入腹腔,富含酶的液体导致继发性“化学性”腹膜炎。在剖腹探查术中进行腹腔穿刺或引流腹水,在某些情况下可使腹水治愈,但通过胰腺囊肿与消化道之间的吻合术(胰-消化道吻合术)进行手术引流,具有确保腹水治疗以及相关胰腺疾病治疗的优势。