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[五种妊娠参考指标预测出生体重不足的诊断准确性]

[Diagnostic accuracy of five gestational references to predict insufficient birth weight].

作者信息

Benjumea María Victoria

机构信息

Grupo de Investigación Materno Perinatal de Caldas, Departamento de Salud Pública, Universidad de Caldas, Manizales, Colombia.

出版信息

Biomedica. 2007 Mar;27(1):42-55. Epub 2007 May 31.

Abstract

INTRODUCTION

The maternal anthropometry is a potentially valuable tool in the evaluation of pregnancy status and prediction of birth weight.

OBJECTIVES

Diagnostic accuracy of birth weight was compared for five gestational anthropometric references.

MATERIALS AND METHODS

Longitudinal study was designed for 245 pregnant Colombian participants. Variables consisted of birth weight, gestational age, maternal height and weight. The references were as follows: gestational weight gain of Fescina (Uruguayan samples), % weight/height and body mass index of Rosso-Mardones (Chilean sample), pregestational weight of the Institute of Medicine (United States sample), and the body mass index of Atalah and colleagues (Chilean sample). The insufficient birth weight (<3,000 g) was defined as the critical threshold value. The following indices, with correspondent confidence intervals (CI 95%) were obtained: diagnostic accuracy, sensitivity, specificity, positive and negative predictive values, and agreement (Kappa index).

RESULTS

The ability to predict the weight <3,000 g was higher in the first trimester measurement with the Chilean references, and in the second trimester with the USA and the Uruguayan references. The best concordance was presented between the Chilean references and the least with the Uruguayan. After the second trimester, the Chilean reference of Atalah and colleagues provided the best diagnostic accuracy, specificity and positive predictive value.

CONCLUSION

The gestational anthropometric references that provided the most heterogeneous results were the US Institute of Medicine and the Fescina. Overall, the Atalah reference was the most accurate diagnostic predictor of insufficient weight at birth.

摘要

引言

孕妇人体测量学是评估妊娠状况和预测出生体重的一项潜在有价值的工具。

目的

比较五种孕期人体测量参考指标对出生体重的诊断准确性。

材料与方法

对245名哥伦比亚孕妇进行纵向研究。变量包括出生体重、孕周、孕妇身高和体重。参考指标如下:费斯纳的孕期体重增加量(乌拉圭样本)、罗索 - 马多内斯的体重/身高百分比和体重指数(智利样本)、美国医学研究所的孕前体重(美国样本)以及阿塔拉及其同事的体重指数(智利样本)。将出生体重不足(<3000克)定义为临界阈值。获得了以下指标及相应的95%置信区间:诊断准确性、敏感性、特异性、阳性和阴性预测值以及一致性(卡帕指数)。

结果

在孕早期测量中,智利参考指标预测体重<3000克的能力较高,在孕中期,美国和乌拉圭参考指标的预测能力较高。智利参考指标之间的一致性最好,与乌拉圭参考指标的一致性最差。孕中期之后,阿塔拉及其同事的智利参考指标提供了最佳的诊断准确性、特异性和阳性预测值。

结论

提供最不一致结果的孕期人体测量参考指标是美国医学研究所和费斯纳的指标。总体而言,阿塔拉参考指标是出生体重不足最准确的诊断预测指标。

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