Alpkvist E, Klapper I
Applied Mathematics Group, School of Technology and Society, Malmö University, SE-20506 Malmö, Sweden.
Water Sci Technol. 2007;55(8-9):265-73. doi: 10.2166/wst.2007.267.
Bacterial biofilms, while made up of microbial-scale objects, also function as meso- and macroscale materials. In particular, macro-scale material properties determine how biofilms respond to large-scale mechanical stresses, e.g. fluid shear. Viscoelastic and other constitutive properties influence biomass structure (through growth and fluid shear stresses) by erosion and sloughing detachment. In this paper, using the immersed boundary method, biofilm is modelled by a system of viscoelastic, breakable springs embedded in a fluid flow, evolving according to the basic physical laws of conservation of mass and momentum. We demonstrate in the context of computer simulation biofilm deformation and detachment under fluid shear stress.
细菌生物膜虽然由微生物尺度的物体组成，但也具有中观和宏观尺度材料的功能。特别是，宏观尺度的材料特性决定了生物膜如何应对大规模的机械应力，例如流体剪切力。粘弹性和其他本构特性通过侵蚀和脱落分离影响生物量结构（通过生长和流体剪切应力）。在本文中，使用浸入边界方法，生物膜由嵌入流体流中的粘弹性、可断裂弹簧系统建模，根据质量和动量守恒的基本物理定律演化。我们在计算机模拟的背景下展示了流体剪切应力下生物膜的变形和分离。
