细针穿刺活检对甲状腺激素水平的影响。
The effects of fine-needle biopsy on thyroid hormone levels.
作者信息
Alpay H Cengiz, Kalidag Turgut, Keles Erol, Kaygusuz Irfan, Yalcin Sinasi, Kapusuz Zeliha
机构信息
Firat University Medical Faculty, Otorhinolaryngology Department, Elaziğ, Turkey.
出版信息
Otolaryngol Head Neck Surg. 2007 Jun;136(6):942-5. doi: 10.1016/j.otohns.2006.12.017.
OBJECTIVE
Our study aim was to investigate the effects of fine-needle biopsy used for thyroid nodules on serum thyroid hormone levels.
STUDY DESIGN
A total of 25 patients who had solid nodules of the thyroid gland and normal thyroid hormone levels underwent diagnostic fine-needle biopsy for a nodule of the thyroid gland.
METHODS
Venous blood samples were drawn from the cases for measurement of serum total T(3) and T(4), free T(3) and T(4), thyroid-stimulating hormone, and thyroglobulin levels before, immediately after, and 30 minutes after the initial biopsy.
RESULTS
Total T(3) and thyroglobulin levels were found to be significantly higher immediately and 30 minutes following fine-needle aspiration biopsy, compared to the baseline levels (P<0.05).
CONCLUSION
Preliminary data suggest that thyroid hormone levels show a mean increase of about 20% immediately after fine-needle aspiration.
SIGNIFICANCE
The implication of this finding on patient care should be determined on an individual basis.
目的
我们的研究目的是调查用于甲状腺结节的细针穿刺活检对血清甲状腺激素水平的影响。
研究设计
共有25例甲状腺实性结节且甲状腺激素水平正常的患者接受了针对甲状腺结节的诊断性细针穿刺活检。
方法
在初次活检前、活检后即刻以及活检后30分钟采集病例的静脉血样本，以测量血清总T(3)、T(4)、游离T(3)和T(4)、促甲状腺激素以及甲状腺球蛋白水平。
结果
与基线水平相比，发现细针穿刺活检后即刻及30分钟时总T(3)和甲状腺球蛋白水平显著升高（P<0.05）。
结论
初步数据表明，细针穿刺后甲状腺激素水平立即平均升高约20%。
意义
这一发现对患者护理的影响应根据个体情况确定。
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