Benito-León J, Martínez-Martín P, Frades B, Martínez-Ginés M L, de Andrés C, Meca-Lallana J E, Antigüedad A R, Huete-Antón B, Rodríguez-García E, Ruiz-Martínez J
Department of Neurology, Móstoles General Hospital, and Gregorio Marañón University, Madrid, Spain.
Mult Scler. 2007 Jun;13(5):645-51. doi: 10.1177/1352458506073528. Epub 2007 Feb 16.
The Fatigue Impact Scale for Daily Use (D-FIS) is an eight-item instrument designed to measure subjective daily experience of fatigue. This study sought to determine the metric properties of the D-FIS in multiple sclerosis (MS) patients.
Sixty-eight patients with operationally-defined MS and fatigue (54.8% of the sample) underwent the D-FIS. Usual clinical measures for MS, the Montgomery-Asberg Depression Rating Scale (MADRS) and the Functional Assessment of Multiple Sclerosis (FAMS) were also applied. In addition, patients with fatigue completed the Fatigue Descriptive Scale, the Multidimensional Fatigue Inventory (MFI), a Visual Analogue Scale for Fatigue (VAS-F), and a Global Perception of Fatigue Scale (GPF).
Full computable data, 95.6%; both floor and ceiling effect=1.54%; item-total correlation=0.62 (item 1) to 0.84 (item 6); Cronbach's alpha=0.91; item homogeneity =0.55; standard error of measurement=3.18; convergent validity with other fatigue measures=-0.57 (VAS-F); 0.52 (GPF); and 0.46 (MFI-general fatigue). Test-retest reliability (ICC)=0.81. There was a strong association between health-related quality of life (HRQoL) (FAMS) and D-FIS (rS=0.70).
In this study, D-FIS proved to be a feasible and valid instrument for measuring MSrelated fatigue, a frequent symptom associated with deterioration of patients' HRQoL.
日常疲劳影响量表（D - FIS）是一个由八个项目组成的工具，旨在测量疲劳的主观日常体验。本研究旨在确定D - FIS在多发性硬化症（MS）患者中的度量特性。
68例经操作定义为患有MS且有疲劳症状的患者（占样本的54.8%）接受了D - FIS测试。还应用了MS的常规临床测量方法，即蒙哥马利 - 阿斯伯格抑郁评定量表（MADRS）和多发性硬化症功能评估量表（FAMS）。此外，有疲劳症状的患者完成了疲劳描述量表、多维疲劳量表（MFI）、疲劳视觉模拟量表（VAS - F）和整体疲劳感知量表（GPF）。
完整可计算数据占95.6%；地板效应和天花板效应均为1.54%；项目 - 总分相关性为0.62（项目1）至0.84（项目6）；克朗巴哈系数α = 0.91；项目同质性为0.55；测量标准误为3.18；与其他疲劳测量方法的收敛效度为 - 0.57（VAS - F）；0.52（GPF）；以及0.46（MFI - 一般疲劳）。重测信度（ICC）= 0.81。健康相关生活质量（HRQoL）（FAMS）与D - FIS之间存在强关联（rS = 0.70）。
在本研究中，D - FIS被证明是一种可行且有效的工具，用于测量与MS相关的疲劳，这是一种与患者HRQoL恶化相关的常见症状。
