Armutlu Kadriye, Keser Ilke, Korkmaz Nilüfer, Akbiyik Derya Iren, Sümbüloğlu Vildan, Güney Zafer, Karabudak Rana
Hacettepe University Physical Therapy and Rehabilitation School, 06100, Samanpazari, and Hacettepe University Hospitals Department of Neurology, Ankara, Turkey.
J Neurol Sci. 2007 Apr 15;255(1-2):64-8. doi: 10.1016/j.jns.2007.01.073. Epub 2007 Mar 6.
The aims of this study were to test the validity, test-retest reliability, and internal consistency of Turkish version of FIS; the variables affecting FIS score.
71 MS patients and 68 healthy subjects were included to the study.
Total FIS score and subscale scores were different statistically between MS patients and healthy volunteers in both first and second FIS applications (p<0.001). These results showed that FIS is validated in divergent direction. BDI score was higher in MS patients than healthy volunteers (p<0.001). There was no statistically significant difference between two study groups for cognitive subscale scores, after the effect of depression was eliminated (p>0.05). To assess the test-retest reliability, the scores of two FIS applications did not differ statistically (cognitive t=1.948 p>0.05, physical t=1.420 p=0.160, social t=1.470 p=0.146, total t=1.990 p=0.05). Intraclass correlation coefficients were 0.89 (99% confidence interval: 0.79-0.94) for cognitive, 0.95 (0.91-0.97) for physical, 0.91 (0.83-0.95) for social, and 0.93 (0.86-0.96) for total FIS scores (p<0.001). EDSS correlated with physical subscores in both applications of FIS.
Turkish version of FIS, which is valid and reliable, seems an appropriate tool for the assessment of the effects of fatigue in Turkish MS population.
本研究旨在测试疲劳影响量表（FIS）土耳其语版本的有效性、重测信度和内部一致性；以及影响FIS评分的变量。
71例多发性硬化症（MS）患者和68名健康受试者纳入本研究。
在FIS首次和第二次应用中，MS患者与健康志愿者之间的FIS总分及各子量表得分均存在统计学差异（p<0.001）。这些结果表明FIS在不同方向上得到了验证。MS患者的贝克抑郁量表（BDI）得分高于健康志愿者（p<0.001）。消除抑郁影响后，两个研究组在认知子量表得分上无统计学显著差异（p>0.05）。为评估重测信度，两次FIS应用的得分无统计学差异（认知t=1.948，p>0.05；身体t=1.420，p=0.160；社会t=1.470，p=0.146；总分t=1.990，p=0.05）。组内相关系数在认知方面为0.89（99%置信区间：0.79 - 0.94），身体方面为0.95（0.91 - 0.97），社会方面为0.91（0.83 - 0.95），FIS总分方面为0.93（0.86 - 0.96）（p<0.001）。在FIS的两次应用中，扩展残疾状态量表（EDSS）与身体子得分均相关。
有效且可靠的FIS土耳其语版本似乎是评估土耳其MS人群疲劳影响的合适工具。
