Hosler Matthew R, Turbin Roger E, Cho Eun-Sook, Wolansky Leo J, Frohman Larry P
Department of Ophthalmology and Visual Science, New Jersey Medical School, Newark, New Jersey 07103, USA.
J Neuroophthalmol. 2007 Jun;27(2):95-8. doi: 10.1097/WNO.0b013e318064c53a.
A 28-year-old woman with a 6-year history of optic neuropathy and 8 years of hearing loss had enhancing dural lesions around the brain stem and in both internal auditory canals on MRI. Histopathology from cranial procedures performed in 1990 and 1993 was originally interpreted as inflammatory meningioma, now known as lymphoplasmacyte-rich meningioma (LRM). Because the clinical course was more consistent with a relapsing process, the original surgical specimens were restudied with additional immunocytochemical stains. The review led to a pathologic diagnosis of idiopathic hypertrophic pachymeningitis (IHP). IHP and LRM can be confused on both imaging and histopathologic grounds.
一名28岁女性，有6年视神经病变病史和8年听力丧失病史，MRI显示脑干周围及双侧内听道有强化的硬脑膜病变。1990年和1993年进行的颅骨手术的组织病理学最初被解释为炎性脑膜瘤，现在称为富含淋巴细胞浆细胞的脑膜瘤（LRM）。由于临床病程更符合复发过程，因此对原始手术标本进行了重新研究，并增加了免疫细胞化学染色。复查结果得出特发性肥厚性硬脑膜炎（IHP）的病理诊断。IHP和LRM在影像学和组织病理学方面都可能混淆。
