Deprez M, Born J, Hauwaert C, Otto B, Reznik M
Department of Neuropathology, Tour de Pathologie-B-35, CHU, Sart-Tilman-Liège, Belgium.
Acta Neuropathol. 1997 Oct;94(4):385-9. doi: 10.1007/s004010050723.
A case of idiopathic hypertrophic cranial pachymeningitis with an unusual and misleading manifestation is reported. Computed tomography scan, angiographic and magnetic resonance imaging findings were suggestive of multiple meningeal neoplasms and a correct diagnosis was made only after meningeal biopsy. This 44-year-old patient had a previous history of an ill-defined systemic disorder associating episcleritis, erythroderma nodosa and multiple peripheral arthritis. We review previous reports of idiopathic cranial pachymeningitis with emphasis on radiological investigation techniques, histopathology and possible dysimmune mechanisms of pathogenesis.
报告了一例具有不寻常且具误导性表现的特发性肥厚性硬脑膜炎病例。计算机断层扫描、血管造影和磁共振成像结果提示为多发性脑膜肿瘤，仅在进行脑膜活检后才做出正确诊断。该44岁患者既往有不明原因的全身性疾病史，伴有巩膜炎、结节性红斑和多发性外周关节炎。我们回顾了特发性硬脑膜炎的既往报告，重点关注放射学检查技术、组织病理学及可能的发病免疫异常机制。
