Levengood J M, Skowron L M
Center for Wildlife and Plant Ecology, Illinois Natural History Survey, 1816 South Oak Street, Champaign, Illinois 61820, USA.
Arch Environ Contam Toxicol. 2007 Aug;53(2):281-6. doi: 10.1007/s00244-005-0324-0. Epub 2007 Jun 1.
Six- to eight-month-old female farm-raised mallards (Anas platyrhynchos) were used to examine the accumulation of and association among cadmium (Cd), zinc (Zn), and copper (Cu) from an impoundment constructed to contain sediments dredged from a lake contaminated by a zinc smelter. Cd was not detectable in the livers t of farm-raised mallards (day 0), although sentinel mallards accumulated hepatic Cd in the first 7 days after release. By day 14, mean concentrations of Cd in kidneys (= 2.82 mg/kg wet weight) had increased 3.4-fold. The mean pancreatic Cd concentration increased 59% between days 7 and 14. Renal Zn increased nominally, whereas pancreatic Zn increased 63% in sentinel ducks after release. Hepatic Zn increased significantly in the first week of release. Renal and pancreatic Cu concentrations did not change significantly, whereas concentrations of Cu in livers of ducks increased 50% in the 7 days after release before decreasing by nearly the same degree. Concentrations of Cd and Zn were correlated in livers of sentinel mallards on days 7 and 14. Cd and Cu were not correlated in the tissues of any cohort. Cu and Zn were correlated in the livers of farm-raised mallards, in the pancreases of sentinel mallards at day 7, and in the kidneys of the ducks in all three treatments. The relationship between Cd and Zn in tissues of ducks in our study was complicated by simultaneous exposure to increased and heterogeneous concentrations of Cd and Zn, both of which can induce metallothionein and compete for this and other ligands.
利用6至8月龄的雌性农场养殖绿头鸭（Anas platyrhynchos），来研究镉（Cd）、锌（Zn）和铜（Cu）在一个蓄水区中的积累情况及其相互关系。该蓄水区是为容纳从受锌冶炼厂污染的湖泊中疏浚的沉积物而建造的。在农场养殖的绿头鸭肝脏中（第0天）未检测到镉，尽管哨兵绿头鸭在放归后的前7天肝脏中积累了镉。到第14天，肾脏中镉的平均浓度（=2.82毫克/千克湿重）增加了3.4倍。胰腺中镉的平均浓度在第7天至第14天之间增加了59%。肾脏中的锌略有增加，而放归后哨兵鸭胰腺中的锌增加了63%。放归后的第一周肝脏中的锌显著增加。肾脏和胰腺中的铜浓度没有显著变化，而鸭子肝脏中的铜浓度在放归后的7天内增加了50%，随后又下降了几乎相同的幅度。在第7天和第14天，哨兵绿头鸭肝脏中镉和锌的浓度呈正相关。在任何一组的组织中，镉和铜都不相关。在农场养殖绿头鸭的肝脏中、第7天哨兵绿头鸭的胰腺中以及所有三种处理方式下鸭子的肾脏中，铜和锌都呈正相关。在我们的研究中，鸭子组织中镉和锌的关系因同时暴露于浓度增加且不均匀的镉和锌而变得复杂，这两种元素都能诱导金属硫蛋白的产生，并竞争这种和其他配体。
