人类和豚鼠耳蜗的低频特性。

Low-frequency characteristics of human and guinea pig cochleae.

作者信息

Marquardt Torsten, Hensel Johannes, Mrowinski Dieter, Scholz Günther

机构信息

UCL Ear Institute, University College London, London WC1X8EE, United Kingdom.

出版信息

J Acoust Soc Am. 2007 Jun;121(6):3628-38. doi: 10.1121/1.2722506.

Abstract

Previous physiological studies investigating the transfer of low-frequency sound into the cochlea have been invasive. Predictions about the human cochlea are based on anatomical similarities with animal cochleae but no direct comparison has been possible. This paper presents a noninvasive method of observing low frequency cochlear vibration using distortion product otoacoustic emissions (DPOAE) modulated by low-frequency tones. For various frequencies (15-480 Hz), the level was adjusted to maintain an equal DPOAE-modulation depth, interpreted as a constant basilar membrane displacement amplitude. The resulting modulator level curves from four human ears match equal-loudness contours (ISO226:2003) except for an irregularity consisting of a notch and a peak at 45 Hz and 60 Hz, respectively, suggesting a cochlear resonance. This resonator interacts with the middle ear stiffness. The irregularity separates two regions of the middle ear transfer function in humans: A slope of 12 dB/octave below the irregularity suggests mass-controlled impedance resulting from perilymph movement through the helicotrema; a 6-dB/octave slope above the irregularity suggests resistive cochlear impedance and the existence of a traveling wave. The results from four guinea pig ears showed a 6-dB/octave slope on either side of an irregularity around 120 Hz, and agree with published data.

摘要

以往研究低频声音传入耳蜗的生理学研究均具有侵入性。关于人类耳蜗的预测是基于与动物耳蜗的解剖学相似性,但无法进行直接比较。本文提出了一种使用由低频音调调制的畸变产物耳声发射(DPOAE)来观察低频耳蜗振动的非侵入性方法。对于各种频率(15 - 480 Hz),调整电平以保持相等的DPOAE调制深度,这被解释为恒定的基底膜位移幅度。来自四只人耳的调制器电平曲线与等响度轮廓(ISO226:2003)相匹配,但存在不规则性,分别在45 Hz和60 Hz处有一个凹口和一个峰值,表明存在耳蜗共振。这种共振器与中耳刚度相互作用。这种不规则性将人类中耳传递函数的两个区域分开:不规则性以下12 dB/倍频程的斜率表明是由外淋巴通过蜗孔移动产生的质量控制阻抗;不规则性以上6 dB/倍频程的斜率表明是电阻性耳蜗阻抗以及行波的存在。来自四只豚鼠耳朵的结果显示,在120 Hz左右的不规则性两侧有6 dB/倍频程的斜率,与已发表的数据一致。

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