综述文章：咖啡对肝脏疾病和肝功能可能的有益作用。
Review article: possible beneficial effects of coffee on liver disease and function.
作者信息
Cadden I S H, Partovi N, Yoshida E M
机构信息
Division of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
出版信息
Aliment Pharmacol Ther. 2007 Jul 1;26(1):1-8. doi: 10.1111/j.1365-2036.2007.03319.x.
BACKGROUND
Coffee is consumed by 50 percent of Americans every day. After oil, coffee is the second most valuable commodity in the world. In recent years a number of studies have suggested potential health risks associated with coffee consumption; however, the results are controversial. Whilst coffee has been reported to increase cardiovascular risk factors, other investigators have demonstrated its protective effects on diseases ranging from type 2 diabetes to Parkinson's disease. A number of investigators have focused their attention on the relationship between the consumption of coffee and liver disease.
AIM
To examine the published literature to date in an attempt to establish the presence of an hepatoprotective effect of coffee.
METHODS
Using PubMed, we identified published studies and review articles relating to the effect of coffee consumption on diseases of the liver.
CONCLUSION
A number of studies have reported the beneficial effects of coffee on abnormal liver biochemistry, cirrhosis and hepatocellular carcinoma. At the present time the mechanism of this effect remains unclear as does the ''dose'' required to achieve these benefits.
背景
50%的美国人每天都喝咖啡。咖啡是仅次于石油的世界第二大最有价值商品。近年来，一些研究表明喝咖啡可能存在健康风险；然而，结果存在争议。虽然有报道称咖啡会增加心血管风险因素，但其他研究人员已证明其对从2型糖尿病到帕金森病等多种疾病具有保护作用。许多研究人员将注意力集中在咖啡消费与肝脏疾病之间的关系上。
目的
审查迄今为止已发表的文献，试图确定咖啡是否具有肝脏保护作用。
方法
我们使用PubMed数据库识别了已发表的关于咖啡消费对肝脏疾病影响的研究和综述文章。
结论
一些研究报告了咖啡对肝脏生化指标异常、肝硬化和肝细胞癌的有益作用。目前，这种作用的机制尚不清楚，实现这些益处所需的“剂量”也不清楚。
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