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关于口臭病因及测量方法的当前文献综述。

A review of the current literature on aetiology and measurement methods of halitosis.

作者信息

van den Broek Annemiek M W T, Feenstra Louw, de Baat Cees

机构信息

Department of Oral and Maxillofacial Surgery and Special Dental Care, Erasmus University Medical Centre, Rotterdam, The Netherlands.

出版信息

J Dent. 2007 Aug;35(8):627-35. doi: 10.1016/j.jdent.2007.04.009. Epub 2007 Jun 6.

Abstract

OBJECTIVES

This work reviews the current knowledge of aetiology and measurement methods of halitosis.

DATA

Halitosis is an unpleasant or offensive odour emanating from the breath. The condition is multifactorial and may involve both oral and non-oral conditions.

SOURCES

A private, monthly with keywords halitosis, malodo(u)r, (a)etiology, measurement, and management from Medline and Pubmed updated database of literature was reviewed.

CONCLUSIONS

In approximately 80-90% of all cases, halitosis is caused by oral conditions, defined as oral malodour. Oral malodour results from tongue coating, periodontal disease, peri-implant disease, deep carious lesions, exposed necrotic tooth pulps, pericoronitis, mucosal ulcerations, healing (mucosal) wounds, impacted food or debris, imperfect dental restorations, unclean dentures, and factors causing decreased salivary flow rate. The basic process is microbial degradation of organic substrates. Non-oral aetiologies of halitosis include disturbances of the upper and lower respiratory tract, disorders of the gastrointestinal tract, some systemic diseases, metabolic disorders, medications, and carcinomas. Stressful situations are predisposing factors. There are three primary measurement methods of halitosis. Organoleptic measurement and gas chromatography are very reliable, but not very easily clinically implemented methods. The use of organoleptic measurement is suggested as the 'gold standard'. Gas chromatography is the preferable method if precise measurements of specific gases are required. Sulphide monitoring is an easily used method, but has the limitation that important odours are not detected. The scientific and practical value of additional or alternative measurement methods, such as BANA test, chemical sensors, salivary incubation test, quantifying beta-galactosidase activity, ammonia monitoring, ninhydrin method, and polymerase chain reaction, has to be established.

摘要

目的

本文综述了当前关于口臭病因及测量方法的知识。

资料

口臭是从口腔呼出的一种令人不悦或有异味的气味。该病症是多因素导致的,可能涉及口腔和非口腔状况。

来源

对从Medline和Pubmed更新文献数据库中检索到的私人月度资料进行了综述,检索词为口臭(halitosis)、恶臭(malodo(u)r)、病因((a)etiology)、测量(measurement)和管理(management)。

结论

在所有病例中,约80% - 90%的口臭由口腔状况引起,即口腔异味。口腔异味源于舌苔、牙周病、种植体周围疾病、深龋病变、暴露的坏死牙髓、冠周炎、黏膜溃疡、愈合中的(黏膜)伤口、嵌塞的食物或碎屑、不完善的牙齿修复体、不洁的假牙以及导致唾液流速降低的因素。基本过程是有机底物的微生物降解。口臭的非口腔病因包括上、下呼吸道疾病、胃肠道疾病、一些全身性疾病、代谢紊乱、药物以及癌症。压力状况是诱发因素。口臭有三种主要测量方法。感官测量和气相色谱法非常可靠,但在临床上不太容易实施。感官测量被建议作为“金标准”。如果需要精确测量特定气体,气相色谱法是更可取的方法。硫化物监测是一种易于使用的方法,但存在无法检测到重要气味的局限性。必须确定其他测量方法或替代测量方法的科学和实用价值,如BANA试验、化学传感器、唾液培养试验、定量β - 半乳糖苷酶活性、氨监测、茚三酮法和聚合酶链反应。

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