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为何人们不按医嘱服用精神药物:2000年全国精神疾病发病率调查结果

Why people do not take their psychotropic drugs as prescribed: results of the 2000 National Psychiatric Morbidity Survey.

作者信息

Cooper C, Bebbington P, King M, Brugha T, Meltzer H, Bhugra D, Jenkins R

机构信息

UCL, Department of Mental Health Sciences, London, UK.

出版信息

Acta Psychiatr Scand. 2007 Jul;116(1):47-53. doi: 10.1111/j.1600-0447.2006.00974.x.

Abstract

OBJECTIVE

We examined the prevalence and determinants of the reasons given for non-adherence to psychiatric medication in a representative community survey.

METHOD

We used data for all participants taking oral psychotropic medication (n = 634) from the 2000 British Survey of National Psychiatric Morbidity.

RESULTS

Of participants interviewed, 217 (34.2%) reported incomplete adherence to their psychiatric medication. Reasons given included forgetting, losing, running out (37.4%); thinking medication unnecessary (24.6%); reluctance to take drugs (18.9%) and side-effects (14.2%). Those giving forgetfulness or side-effects as reasons were younger. Side-effects were reported more frequently by people with a lower IQ or with psychosis. Those taking Selective Serotonin Reuptake Inhibitors were more likely to forget to take their medication.

CONCLUSION

Two-fifths of people reported that missing their medication was a decision taken because they did not want it or think it necessary. Side-effects are a relatively uncommon reason for under-medication. Our results have implications for interventions to assist adherence.

摘要

目的

在一项具有代表性的社区调查中,我们研究了不坚持服用精神科药物的原因的患病率及其决定因素。

方法

我们使用了2000年英国全国精神疾病调查中所有服用口服精神药物的参与者(n = 634)的数据。

结果

在接受访谈的参与者中,217人(34.2%)报告未完全坚持服用精神科药物。给出的原因包括忘记、丢失、用完药物(37.4%);认为药物不必要(24.6%);不愿服药(18.9%)和副作用(14.2%)。以忘记或副作用为原因的人更年轻。智商较低或患有精神病的人报告副作用的频率更高。服用选择性5-羟色胺再摄取抑制剂的人更有可能忘记服药。

结论

五分之二的人报告说,漏服药物是因为他们不想服用或认为没有必要而做出的决定。副作用是药物服用不足的相对不常见原因。我们的结果对协助坚持服药的干预措施具有启示意义。

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