Walker S J, Allen S M, Steel A, Cullen M H, Matthews H R
Regional Department of Thoracic Surgery, East Birmingham Hospital, UK.
Eur J Cardiothorac Surg. 1991;5(10):519-22. doi: 10.1016/1010-7940(91)90104-r.
Thirty-eight patients with localised oesophageal carcinoma have been studied by computed tomography (CT) and barium swallow before and after preoperative chemotherapy and the results correlated with the pathological findings in the resected specimen. Overall 48% of patients showed a complete or partial response to chemotherapy on CT, compared with 50% on barium and 94% on pathological examination. This study highlights deficiencies in CT scanning and barium swallow as methods of assessing the regression of tumor bulk following chemotherapy for oesophageal carcinoma. We suggest that strict and specific criteria will have to be laid down before the results of chemotherapy in this disease can be reliably and accurately evaluated.
对38例局限性食管癌患者在术前化疗前后进行了计算机断层扫描（CT）和钡餐检查，并将结果与切除标本的病理检查结果进行了对比。总体而言，48%的患者在CT上显示对化疗有完全或部分反应，钡餐检查为50%，病理检查为94%。这项研究突出了CT扫描和钡餐检查作为评估食管癌化疗后肿瘤体积消退方法的不足之处。我们建议，在能够可靠且准确地评估这种疾病的化疗结果之前，必须制定严格且具体的标准。
