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美国接种疫苗后发生的吉兰-巴雷综合征——来自美国疾病控制与预防中心/美国食品药品监督管理局疫苗不良事件报告系统的一份报告

Guillain-Barre syndrome after vaccination in United States a report from the CDC/FDA Vaccine Adverse Event Reporting System.

作者信息

Souayah Nizar, Nasar Abu, Suri M Fareed K, Qureshi Adnan I

机构信息

Epidemiological and Outcomes Research Division, Zeenat Qureshi Stroke Research Center, Department of Medicine, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, DOC 8100, Newark, NJ 07103, United States.

出版信息

Vaccine. 2007 Jul 20;25(29):5253-5. doi: 10.1016/j.vaccine.2007.03.053. Epub 2007 May 22.

Abstract

Using the data from Vaccine Adverse Event Reporting System, we present 54 reports of Guillain-Barre Syndrome (GBS) after vaccination that occurred in United States in 2004. In 38 of the patients, GBS occurred within 6 weeks. The highest number (n=31) of GBS was observed in patients receiving influenza vaccine followed by hepatitis vaccine (n=9), 1 patient died and 10 patients were disabled following the event. We conclude that vaccines other than influenza vaccine can be associated with GBS.

摘要

利用疫苗不良事件报告系统的数据,我们呈现了2004年在美国发生的54例接种疫苗后出现格林-巴利综合征(GBS)的报告。在38例患者中,GBS在6周内发生。接受流感疫苗的患者中观察到的GBS病例数最多(n = 31),其次是肝炎疫苗(n = 9),事件发生后1例患者死亡,10例患者致残。我们得出结论,除流感疫苗外的其他疫苗也可能与GBS有关。

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