Dwyer T, Ponsonby A L, Gibbons L E, Newman N M
Menzies Centre for Population Health Research, Hobart, Tasmania, Australia.
J Paediatr Child Health. 1991 Dec;27(6):340-3. doi: 10.1111/j.1440-1754.1991.tb00415.x.
The most recent data from the cohort and case-control studies of SIDS and prone position recently reported from Tasmania are reviewed. The cohort analysis was based on 4103 infants born between 1 January 1988 and 1 December 1990 assessed as being at high risk at birth, of whom 29 later died of SIDS. A matched analysis which controlled for infant birthweight and maternal age indicated that prone sleeping position was associated with an increased risk of SIDS (OR 3.92, 95% Cl [1.37-11.24]). The case-control study was based on all (n = 55) Tasmanian SIDS death from October 1989 to April 1991 and matched live controls. The unadjusted odds ratio for prone position and SIDS was 5.04 (95% Cl [2.29-11.11]). The population attributable risk percentage, based on the high risk cohort data, was 0.38 (95% Cl [0.35-0.41]), suggesting that a significant reduction in SIDS incidence might occur if the prevalence of the prone sleeping position in the infant population were reduced. Other factors which may be important for the development of any public health interventions to reduce SIDS based on these findings are discussed.
本文回顾了塔斯马尼亚岛最近报告的关于婴儿猝死综合征（SIDS）与俯卧位的队列研究和病例对照研究的最新数据。队列分析基于1988年1月1日至1990年12月1日期间出生的4103名婴儿，这些婴儿在出生时被评估为高危婴儿，其中29名后来死于婴儿猝死综合征。一项对婴儿出生体重和母亲年龄进行控制的匹配分析表明，俯卧睡眠姿势与婴儿猝死综合征风险增加有关（比值比3.92，95%可信区间[1.37 - 11.24]）。病例对照研究基于1989年10月至1991年4月期间塔斯马尼亚岛所有（n = 55）婴儿猝死综合征死亡病例以及匹配的存活对照。俯卧位与婴儿猝死综合征的未调整比值比为5.04（95%可信区间[2.29 - 11.11]）。基于高危队列数据的人群归因风险百分比为0.38（95%可信区间[0.35 - 0.41]），这表明如果婴儿群体中俯卧睡眠姿势的流行率降低，婴儿猝死综合征的发病率可能会显著降低。本文还讨论了基于这些研究结果制定任何减少婴儿猝死综合征公共卫生干预措施时可能重要的其他因素。
