Hsu Shih-Chieh, Liu Chia-Yih, Hsiao Mei-Chun
Department of Psychiatry, Chang-Gung Memorial Hospital and School of Medicine Chang-Gung University, Tao-Yuan 333, Taiwan.
Compr Psychiatry. 2007 Jul-Aug;48(4):366-70. doi: 10.1016/j.comppsych.2007.02.006. Epub 2007 May 24.
Numerous symptoms of premenstrual dysphoric disorder (PMDD) overlap with those of major depressive disorder (MDD). This study investigates differences in novelty seeking, harm avoidance, and reward dependence between patients with PMDD, MDD without premenstrual symptoms or premenstrual exacerbation, and normal control subjects.
The Chinese version of the Tridimensional Personality Questionnaire was administered to 51 PMDD, 39 MDD, and 52 normal control women during the luteal phase (between the menstrual cycle days 23 and 28).
Harm avoidance score was significantly higher in women with MDD and PMDD than in controls, whereas reward dependence score was lower in women with MDD than in controls. However, Tridimensional Personality Questionnaire (except for the subscale of impulsiveness) did not distinguish between PMDD and MDD during the luteal phase.
The similarities between PMDD and MDD during luteal phase suggest a similar psychopathology.
经前烦躁障碍(PMDD)的众多症状与重度抑郁症(MDD)的症状重叠。本研究调查了PMDD患者、无经前症状或经前加重的MDD患者以及正常对照受试者在寻求新奇、回避伤害和奖赏依赖方面的差异。
在黄体期(月经周期的第23至28天),对51名PMDD患者、39名MDD患者和52名正常对照女性进行了中文版三维人格问卷测试。
MDD和PMDD女性的回避伤害得分显著高于对照组,而MDD女性的奖赏依赖得分低于对照组。然而,在黄体期,三维人格问卷(冲动性分量表除外)无法区分PMDD和MDD。
黄体期PMDD和MDD之间的相似性表明存在相似的精神病理学特征。