Bassotti G, Betti C, Erbella G S, Cavalletti M L, Pelli M A, Morelli A
Laboratorio di Motilità Intestinale, Università di Perugia, Italy.
Ital J Gastroenterol. 1991 Nov;23(8 Suppl 1):13-5.
We studied the whole colonic motility for 24 hours in controls and in constipated patients. In the patient group we found a significant reduction in the colonic mass movements (6.1 +/- 0.9 vs 2.6 +/- 0.7 controls vs patients, respectively). The constipated patients showed a reduction of the colonic motor activity after the ingestion of a standard meal. Moreover, they showed, compared with controls, a significant reduction of postprandial mass movements. On the other hand we were not able to find the so-called rectal motor complex described by others. In conclusion, we believe that prolonged colonic manometry would become an important step when evaluating the pathophysiology of constipated patients, particularly of those not responding to standard treatment.
我们在对照组和便秘患者中对整个结肠动力进行了24小时的研究。在患者组中,我们发现结肠集团运动显著减少(对照组与患者组分别为6.1±0.9次与2.6±0.7次)。便秘患者在摄入标准餐后结肠运动活性降低。此外,与对照组相比,他们的餐后集团运动显著减少。另一方面,我们未能发现其他人所描述的所谓直肠运动复合体。总之,我们认为,在评估便秘患者尤其是那些对标准治疗无反应的患者的病理生理学时,延长结肠测压将成为重要的一步。