乳糜泻患者空肠黏膜γ-谷氨酰转移酶活性
Jejunal mucosal gamma glutamyl transferase activity in coeliac disease.
作者信息
Fairman M J, Scott B B, Toothill C, Losowsky M S
出版信息
Gut. 1977 Jun;18(6):484-7. doi: 10.1136/gut.18.6.484.
Abstract
In view of data suggesting that deficiency of gamma glutamyl transferase (GGT) may be the primary abnormality in the small-intestinal mucosa of patients with coeliac disease, this enzyme was measured in mucosal biopsies from coeliac patients at different stages of treatment. Activity was only slightly reduced in only one of nine well-treated patients, suggesting that deficiency of this enzyme has no primary role in the aetiology of coeliac disease.
摘要
鉴于有数据表明γ-谷氨酰转移酶（GGT）缺乏可能是乳糜泻患者小肠黏膜的主要异常情况，我们对处于不同治疗阶段的乳糜泻患者的黏膜活检样本进行了该酶的检测。在九名病情得到良好控制的患者中，只有一人的酶活性略有降低，这表明该酶缺乏在乳糜泻病因中并非主要因素。
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