Chauvet J, Rouille Y, Michel G, Ouedraogo Y, Acher R
Laboratoire de Chimie biologique, Université de Paris-VI, C.N.R.S. (SDI 5662).
C R Acad Sci III. 1991;313(8):353-8.
Occurrence of hydrin 2 (vasotocinyl-glycine), an intermediate in the provasotocin processing, has been shown in the neurointermediate lobe of the pituitary of semi-aquatic or terrestrial amphibian species belonging to the order Anura, namely Rana esculenta, R. temporaria, R. pipiens (Ranidae), and Bufo bufo, B. marinus, B. ictericus (Bufonidae). In contrast hydrin 2 appears absent in species belonging to the order Urodela, namely the axolotl Ambystoma mexicanum (Ambystomidae) and the pleurodele newt, Pleurodela waltlii (Salamandridae). Whereas water transport through the skin and the urinary bladder is stimulated by vasotocin and hydrin 2 in anuran species, this stimulation is known not to occur in urodele species.
催产素原加工过程中的中间体——2-羟赖氨酸(血管紧张素-甘氨酸)已在无尾目半水生或陆生两栖动物垂体的神经中间叶中被发现,这些动物包括食用蛙(蛙科)、欧洲林蛙、北美豹蛙,以及蟾蜍科的中华大蟾蜍、海蟾蜍和黄腹蟾蜍。相比之下,在有尾目动物中未发现2-羟赖氨酸,如有美西钝口螈(钝口螈科)和瓦氏真螈(蝾螈科)。在无尾目动物中,血管紧张素和2-羟赖氨酸可刺激皮肤和膀胱的水运输,但在有尾目动物中这种刺激作用并不存在。