Banno Katsuhisa, Walld Randy, Kryger Meir H
Sleep Disorders Centre, St. Boniface General Hospital, Winnipeg, MB, Canada.
J Clin Sleep Med. 2005 Oct 15;1(4):364-6.
The prevalence of sleep-related breathing disorders (SBD) is high and may be rising because of the increasing prevalence of obesity. We investigated the obesity trends over 9 years in patients referred to a sleep disorders center suspected of having SBD.
There were 5163 new patients (3679 men and 1484 women) who were referred to sleep disorders centee for an assessment of SBD from January 1995 to May 2004.
During the entire period, the mean body mass index (BMI) at time of referral was 32.2 +/- 0.1 kg/m2 (+/- SEM) (95% confidence interval [CI]:32.0-32.4) in men versus 34.5 +/- 0.2 kg/m2 (95% CI: 34.1-35.0) in women (p < .0001). Mean age and BMI were calculated for each 3-month period starting in January 1995. Regression analysis using a generalized linear model was performed to determine the relationship between BMI and the time when the patients were referred, for both sexes. The annual increase in mean BMI was 0.17 (95% CI: 0.10-0.24) for men (p < .0001) and 0.34 (95% CI: 0.13-0.54) for women (p = .002). There was no relationship between age at referral and BMI in either sex. There was a significant positive correlation between year of referral and BMI for both sexes: p < .0001, r2 = 0.40 for men, p = .002, r2 = 0.24 for women. The average female patient was 3.4 BMI units heavier over the 9-year period, while the average male patient was 1.7 BMI units heavier.
The BMI in patients referred to a sleep disorders center for an assessment of SBD has increased significantly over 9 years. Recent obesity trends may contribute to the increase in the number of patients with SBD.
睡眠相关呼吸障碍（SBD）的患病率很高，且由于肥胖患病率的上升可能还在增加。我们调查了9年间被转诊至睡眠障碍中心、疑似患有SBD的患者的肥胖趋势。
1995年1月至2004年5月期间，共有5163名新患者（3679名男性和1484名女性）被转诊至睡眠障碍中心以评估SBD。
在整个研究期间，男性患者转诊时的平均体重指数（BMI）为32.2±0.1kg/m²（±标准误）（95%置信区间[CI]：32.0 - 32.4），女性为34.5±0.2kg/m²（95%CI：34.1 - 35.0）（p <.0001）。从1995年1月开始，每3个月计算一次平均年龄和BMI。使用广义线性模型进行回归分析，以确定男女BMI与患者转诊时间之间的关系。男性的平均BMI年增长率为0.17（95%CI：0.10 - 0.24）（p <.0001），女性为0.34（95%CI：0.13 - 0.54）（p =.002）。转诊时的年龄与男女的BMI均无关联。男女的转诊年份与BMI之间均存在显著正相关：男性p <.0001，r² = 0.40；女性p =.002，r² = 0.24。在9年期间，女性患者的平均BMI比男性患者高3.4个单位，男性患者平均高1.7个单位。
9年间，被转诊至睡眠障碍中心评估SBD的患者的BMI显著增加。近期的肥胖趋势可能导致SBD患者数量增加。
