Partial trisomy 1q. A nonrandom primary chromosomal abnormality in myelodysplastic syndromes?
作者信息
Fonatsch C, Haase D, Freund M, Bartels H, Tesch H
机构信息
Institut für Humangenetik, Medizinische Universität zu Lübeck, Germany.
出版信息
Cancer Genet Cytogenet. 1991 Oct 15;56(2):243-53. doi: 10.1016/0165-4608(91)90177-v.
PMID:1756470
Abstract
Cytogenetic and clinical data of 11 patients with de novo myelodysplastic syndromes and partial or total trisomy of the long arm of chromosome 1 are presented. In eight of these patients trisomy 1q was the sole karyotypic change and therefore can be classified as a primary chromosome anomaly. A remarkably young median age of 36.5 years was noticed in this patient group.
摘要
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