Duquesnoy B
Baillieres Clin Rheumatol. 1991 Aug;5(2):253-61. doi: 10.1016/s0950-3579(05)80282-1.
Henoch-Schönlein purpura probably results from a reaction in a host sensitized by an infective stimulus. This stimulus leads to the synthesis of IgA antibody, the presence of circulating immune complexes and a leukoclastic vasculitis involving IgA resulting in renal and dermatological manifestations. The risk factors, the causal organism and the reason for the association with IgA nephropathy remain unknown.
过敏性紫癜可能是由感染刺激致敏的宿主发生的反应所致。这种刺激导致IgA抗体的合成、循环免疫复合物的存在以及累及IgA的白细胞破碎性血管炎，从而引发肾脏和皮肤表现。其危险因素、致病微生物以及与IgA肾病相关联的原因仍不明确。
