组织因子-因子VIIa复合物：促凝血活性、调节及多功能作用
The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking.
作者信息
Monroe D M, Key N S
机构信息
Center for Thrombosis and Hemostasis, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
出版信息
J Thromb Haemost. 2007 Jun;5(6):1097-105. doi: 10.1111/j.1538-7836.2007.02435.x.
Abstract
Greater understanding of the cellular interactions associated with tissue factor (TF), activated factor (F) VII and TF-FVIIa complexes is likely to provide considerable clinical benefit. This article reviews current knowledge on the function and regulation of TF and its role in a range of biological processes, including hemostasis, thrombosis and inflammation.
摘要
对与组织因子（TF）、活化因子（F）VII 以及 TF-FVIIa 复合物相关的细胞相互作用有更深入的了解，可能会带来可观的临床益处。本文综述了关于 TF 的功能与调控及其在包括止血、血栓形成和炎症在内的一系列生物学过程中所起作用的现有知识。
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