Kaiser Alexander, Krüger Jan, Evers Dirk J
Faculty of Technology, Center for Biotechnology, Bielefeld University, 33594 Bielefeld, Germany.
Nucleic Acids Res. 2007 Jul;35(Web Server issue):W330-4. doi: 10.1093/nar/gkm309. Epub 2007 Jun 12.
RNA Movies is a simple, yet powerful visualization tool in likeness to a media player application, which enables to browse sequential paths through RNA secondary structure landscapes. It can be used to visualize structural rearrangement processes of RNA, such as folding pathways and conformational switches, or to browse lists of alternative structure candidates. Besides extending the feature set, retaining and improving usability and availability in the web is the main aim of this new version. RNA Movies now supports the DCSE and RNAStructML input formats besides its own RNM format. Pseudoknots and 'entangled helices' can be superimposed on the RNA secondary structure layout. Publication quality output is provided through the Scalable Vector Graphics output format understood by most current drawing programs. The software has been completely re-implemented in Java to enable pure client-side operation as applet and web-start application available at the Bielefeld Bioinformatics Server http://bibiserv.techfak.uni-bielefeld.de/rnamovies.
RNA Movies是一个类似于媒体播放器应用程序的简单但功能强大的可视化工具，它能够浏览RNA二级结构景观中的连续路径。它可用于可视化RNA的结构重排过程，如折叠途径和构象转换，或浏览替代结构候选列表。除了扩展功能集外，在网络中保留并提高可用性和易用性是这个新版本的主要目标。RNA Movies现在除了支持其自身的RNM格式外，还支持DCSE和RNAStructML输入格式。假结和“缠结螺旋”可以叠加在RNA二级结构布局上。通过大多数当前绘图程序都能理解的可缩放矢量图形输出格式提供高质量的出版物输出。该软件已完全用Java重新实现，以实现作为小程序和网络启动应用程序的纯客户端操作，可在比勒费尔德生物信息学服务器http://bibiserv.techfak.uni-bielefeld.de/rnamovies上获取。
