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小脑疾病的单光子发射计算机断层扫描(SPECT):大脑小脑性失联络

Single photon emission computed tomography (SPECT) in cerebellar disease: cerebello-cerebral diaschisis.

作者信息

Botez M I, Léveillé J, Lambert R, Botez T

机构信息

Neurology Service, Hôtel-Dieu de Montréal, Canada.

出版信息

Eur Neurol. 1991;31(6):405-12. doi: 10.1159/000116705.

DOI:10.1159/000116705
PMID:1756768
Abstract

Single photon emission computed tomography assessments were conducted in normal controls (n = 25), patients with unilateral cerebellar infarctions (n = 4), patients with olivopontocerebellar atrophy (OPCA; n = 15) and patients with Friedreich's ataxia (FA; n = 6). In subjects with unilateral cerebellar infarctions, crossed cerebellar-cortical diaschisis was observed: reduced cerebellar hexamethylpropyleneamine oxime (HMPAO) uptake was invariably accompanied by a diminution of HMPAO in the contralateral basal ganglia and frontoparietal cortex. OPCA and FA patients had various degrees of decreased HMPAO uptake in both the cerebellum and cerebral hemispheres.

摘要

对正常对照组(n = 25)、单侧小脑梗死患者(n = 4)、橄榄体脑桥小脑萎缩(OPCA;n = 15)患者和弗里德赖希共济失调(FA;n = 6)患者进行了单光子发射计算机断层扫描评估。在单侧小脑梗死患者中,观察到交叉性小脑 - 皮质失联络:小脑六甲基丙烯胺肟(HMPAO)摄取减少总是伴随着对侧基底神经节和额顶叶皮质中HMPAO的减少。OPCA和FA患者的小脑和大脑半球均有不同程度的HMPAO摄取减少。

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