Gómez Beldarrain M, García-Moncó J C, Quintana J M, Llorens V, Rodeño E
Department of Neurology, Hospital de Galdácano, Spain.
Eur Neurol. 1997;37(2):82-9. doi: 10.1159/000117415.
The cerebellum has been implicated in higher-order behavior. Blood flow studies (SPECT) have shown that cerebral diaschisis can appear after cerebellar lesions and this phenomenon could serve as a basis for a potential neuropsychological derangement after cerebellar insults. Our objectives in this study were to delineate the neuropsychological profile after cerebellar stroke, to evaluate cerebral diaschisis as measured by SPECT and to correlate the findings. We prospectively studied 26 patients with cerebellar stroke and 16 subjects matched for age, sex and educational level as a control group. A neuropsychological battery test, MRI and cerebral SPECT were performed in both groups. We found that cerebellar stroke results in motor control impairment and mild naming deficit, whereas no dysfunction in declarative memory, language, visuospatial or executive abilities is evident. The anatomical distribution of the lesion does not seem relevant in terms of neuropsychological impairment or diaschisis. Both ipsilateral and contralateral diaschisis as a result of a cerebellar stroke are found, but this phenomenon does not seem to result in overt neuropsychological derangement.
小脑与高阶行为有关。血流研究（单光子发射计算机断层扫描）表明，小脑损伤后可出现大脑远隔性机能障碍，这种现象可能是小脑损伤后潜在神经心理紊乱的基础。本研究的目的是描绘小脑卒中后的神经心理特征，评估通过单光子发射计算机断层扫描测量的大脑远隔性机能障碍，并将研究结果进行关联分析。我们前瞻性地研究了26例小脑卒中和16例年龄、性别和教育水平相匹配的受试者作为对照组。两组均进行了神经心理成套测试、磁共振成像和脑单光子发射计算机断层扫描。我们发现，小脑卒中会导致运动控制障碍和轻度命名缺陷，而陈述性记忆、语言、视觉空间或执行能力方面没有明显功能障碍。就神经心理损伤或远隔性机能障碍而言，病变的解剖分布似乎无关紧要。发现小脑卒中会导致同侧和对侧远隔性机能障碍，但这种现象似乎不会导致明显的神经心理紊乱。
