Mathias Richard T, Kistler Joerg, Donaldson Paul
Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York, NY 11794-8661, USA.
J Membr Biol. 2007 Mar;216(1):1-16. doi: 10.1007/s00232-007-9019-y. Epub 2007 Jun 14.
The lens is the largest organ in the body that lacks a vasculature. The reason is simple: blood vessels scatter and absorb light while the physiological role of the lens is to be transparent so it can assist the cornea in focusing light on the retina. We hypothesize this lack of blood supply has led the lens to evolve an internal circulation of ions that is coupled to fluid movement, thus creating an internal micro-circulatory system, which makes up for the lack of vasculature. This review covers the membrane transport systems that are believed to generate and direct this internal circulatory system.
晶状体是人体中最大的无血管器官。原因很简单：血管会散射和吸收光线，而晶状体的生理作用是保持透明，以便协助角膜将光线聚焦在视网膜上。我们推测，这种缺乏血液供应的情况促使晶状体进化出一种与液体流动相关的离子内部循环，从而形成一个内部微循环系统，以弥补血管系统的缺失。本综述涵盖了据信能产生并引导这种内部循环系统的膜转运系统。
