Borrajo Jacinto P, Serra Julia, González Pío, León Betty, Muñoz Fernando M, López M
Departamento de Física Aplicada, ETSE Industriais e Minas, Lagoas-Marcosende, Universidade de Vigo, Vigo 36200, Spain.
J Mater Sci Mater Med. 2007 Dec;18(12):2371-6. doi: 10.1007/s10856-007-3153-z. Epub 2007 Jun 14.
During the past years, different techniques, like chemical treatment, plasma spraying, sputtering, enamelling or sol-gel; and materials, like metals, hydroxylapatite, calcium phosphates, among others, have been applied in different combinations to improve the performance of prostheses. Among the techniques, Pulsed Laser Deposition (PLD) is very promising to produce coatings of bioactive glass on any metal alloy used as implant. In this work the biocompatibility of PLD coatings deposited on titanium substrates was examined by implantation in vivo. Different coating compositions were checked to find the most bioactive that was then applied on titanium and implanted into paravertebral muscle of rabbit.
在过去几年中，不同的技术，如化学处理、等离子喷涂、溅射、搪瓷或溶胶 - 凝胶法；以及材料，如金属、羟基磷灰石、磷酸钙等，已被以不同组合应用于改善假体性能。在这些技术中，脉冲激光沉积（PLD）在用于植入物的任何金属合金上制备生物活性玻璃涂层方面非常有前景。在这项工作中，通过体内植入来检查沉积在钛基材上的PLD涂层的生物相容性。检查了不同的涂层成分以找到最具生物活性的成分，然后将其应用于钛并植入兔的椎旁肌中。
