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使用蒙特卡罗方法和基于三维弦的传输技术计算α粒子对人体骨骼组织的吸收分数。

Calculation of absorbed fractions to human skeletal tissues due to alpha particles using the Monte Carlo and 3-D chord-based transport techniques.

作者信息

Hunt J G, Watchman C J, Bolch W E

机构信息

Institute of Radiation Protection and Dosimetry, Av. Salvador Allende s/n, Recreio, Rio de Janeiro, CEP 22780-160, Brazil.

出版信息

Radiat Prot Dosimetry. 2007;127(1-4):223-6. doi: 10.1093/rpd/ncm276. Epub 2007 Jun 14.

Abstract

Absorbed fraction (AF) calculations to the human skeletal tissues due to alpha particles are of interest to the internal dosimetry of occupationally exposed workers and members of the public. The transport of alpha particles through the skeletal tissue is complicated by the detailed and complex microscopic histology of the skeleton. In this study, both Monte Carlo and chord-based techniques were applied to the transport of alpha particles through 3-D microCT images of the skeletal microstructure of trabecular spongiosa. The Monte Carlo program used was 'Visual Monte Carlo--VMC'. VMC simulates the emission of the alpha particles and their subsequent energy deposition track. The second method applied to alpha transport is the chord-based technique, which randomly generates chord lengths across bone trabeculae and the marrow cavities via alternate and uniform sampling of their cumulative density functions. This paper compares the AF of energy to two radiosensitive skeletal tissues, active marrow and shallow active marrow, obtained with these two techniques.

摘要

由于α粒子对人类骨骼组织的吸收分数(AF)计算,对于职业暴露工人和公众的体内剂量测定具有重要意义。α粒子在骨骼组织中的传输因骨骼详细而复杂的微观组织学而变得复杂。在本研究中,蒙特卡罗方法和弦基技术都被应用于α粒子在三维显微CT图像的小梁海绵骨骨骼微结构中的传输。所使用的蒙特卡罗程序是“可视化蒙特卡罗-VMC”。VMC模拟α粒子的发射及其随后的能量沉积轨迹。应用于α传输的第二种方法是弦基技术,它通过对骨小梁和骨髓腔的累积密度函数进行交替和均匀采样,随机生成穿过它们的弦长。本文比较了用这两种技术获得的能量对两种放射敏感骨骼组织,即活跃骨髓和浅表活跃骨髓的吸收分数。

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