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基于NORMAN - 05体素模型的蒙特卡罗N粒子输运程序(MCNPX)内照射剂量学研究

MCNPX internal dosimetry studies based on the NORMAN-05 voxel model.

作者信息

Ferrari P, Gualdrini G

机构信息

ENEA-BAS-ION-Radiation Protection Institute, 16 V.dei Colli, 40136 Bologna (BO), Italy.

出版信息

Radiat Prot Dosimetry. 2007;127(1-4):209-13. doi: 10.1093/rpd/ncm273. Epub 2007 Jun 14.

DOI:10.1093/rpd/ncm273
PMID:17569686
Abstract

Anthropomorphic computational models coupled with radiation transport codes are valuable tools in radiation protection dosimetry. In particular, they are very reliable for the estimate of the energy absorbed by different organs due to an incorporated radionuclide. MIRD-based stylised analytical models are widely accepted as standards but the recent generation of voxel phantoms, developed on real anatomical data derived from tomographic images, can represent a valid alternative for radiation protection and dosimetry purposes. Specific absorbed fraction evaluation and patient-specific dose estimate in nuclear medicine and radiotherapy could be considered as the optimal area for their implementation and use. On the other hand, the accuracy of organ and body structure representation guarantees an improved dose evaluation system also for radiation protection purposes in the workplace in case of accidental internal contamination. In the present work the voxel model NORMAN-05, a modified version of NORMAN (HPA, UK) model, has been employed with the Monte Carlo code MCNPX. Some preliminary investigations were carried out to evaluate the absorbed fractions for a series of source-target organ couples in case of gamma emitters and the organ absorbed doses in case of 90Sr incorporation. The paper summarises the main preliminary outcomes of such studies.

摘要

与辐射传输代码相结合的人体计算模型是辐射防护剂量学中的宝贵工具。特别是,对于估算由于掺入放射性核素而被不同器官吸收的能量,它们非常可靠。基于MIRD的程式化分析模型被广泛接受为标准,但最近基于断层图像得出的真实解剖数据开发的体素体模,对于辐射防护和剂量学目的而言,可以成为一种有效的替代方案。核医学和放射治疗中特定吸收分数的评估以及针对患者的剂量估算可被视为其实施和应用的最佳领域。另一方面,器官和身体结构表示的准确性也确保了在工作场所发生意外内部污染时,用于辐射防护目的的剂量评估系统得到改进。在本工作中,体素模型NORMAN - 05(英国健康保护局NORMAN模型的修改版本)已与蒙特卡罗代码MCNPX一起使用。进行了一些初步研究,以评估在存在伽马发射体的情况下一系列源 - 靶器官对的吸收分数,以及在掺入90Sr的情况下器官的吸收剂量。本文总结了这些研究的主要初步结果。

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