Lizardi Patricia Sánchez, O'Rourke Mary Kay, Morris Richard J
Pupil Services and Special Education, Chula Vista Elementary School District, 84 E J Street, Chula Vista, CA 91910, USA.
J Pediatr Psychol. 2008 Jan-Feb;33(1):91-101. doi: 10.1093/jpepsy/jsm047. Epub 2007 Jun 14.
This study investigates the effects of Organophosphate (OP) pesticides exposure on the cognitive and behavioral functioning of Hispanic children living in an agricultural community.
Forty-eight children were administered a battery of cognitive measures, and their parents and teachers completed behavior rating scales. Children provided a urine sample for analysis of OP pesticides metabolites.
All children had a detectable level of at least one OP pesticide metabolite. Higher OP pesticide metabolite concentration levels were significantly correlated with poorer performance on some subtests of the Wisconsin Card Sorting Test. However, the significance of this association was dependent upon the inclusion of two samples with noticeable higher OP pesticide metabolite concentration levels.
Short-term OP pesticide exposure seems to have deleterious effects on children's speed of attention, sequencing, mental flexibility, visual search, concept formation, and conceptual flexibility. This study is among a relatively small number of studies investigating an extremely complex problem. Limitations and suggestions for future studies are discussed.
本研究调查有机磷（OP）农药暴露对生活在农业社区的西班牙裔儿童认知和行为功能的影响。
对48名儿童进行了一系列认知测试，他们的父母和教师完成了行为评定量表。儿童提供尿液样本用于分析OP农药代谢物。
所有儿童至少有一种OP农药代谢物的可检测水平。较高的OP农药代谢物浓度水平与威斯康星卡片分类测验某些子测验的较差表现显著相关。然而，这种关联的显著性取决于纳入两个OP农药代谢物浓度水平明显较高的样本。
短期接触OP农药似乎对儿童的注意力速度、排序、心理灵活性、视觉搜索、概念形成和概念灵活性有有害影响。本研究是调查一个极其复杂问题的相对少数研究之一。讨论了局限性和对未来研究的建议。
