Keeley Philip, Creed Francis, Tomenson Barbara, Todd Chris, Borglin Gunilla, Dickens Chris
Department of Nursing, Midwifery & Social Work, Coupland III Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK.
Pain. 2008 Mar;135(1-2):142-50. doi: 10.1016/j.pain.2007.05.015. Epub 2007 Jul 3.
Psychological and social factors have been shown, separately, to predict outcome in individuals with chronic low back pain. Few previous studies, however, have integrated both psychological and social factors, using prospective study of clinic populations of low back pain patients, to identify which are the most important targets for treatment. One hundred and eight patients with chronic low back pain, newly referred to an orthopaedic outpatient clinic, completed assessments of demographic characteristics, details of back pain, measures of anxiety and depression (Hospital Anxiety and Depression Scale, HADS), fearful beliefs about pain (Fear Avoidance Beliefs Questionnaire), social stresses (Life Events and Difficulties Schedule) and physical aspects of health-related quality of life [SF-36 Physical Component summary Score scale (PCS)]. Six months later subjects completed the SF-36 PCS and the number of healthcare contacts during follow-up was recorded. Independent predictors of SF-36 PCS at 6-month follow-up were duration of pain [(standardised regression coefficient (beta)=-0.18, p=0.04), HADS score (beta)=-0.27, p=0.003] and back pain related social difficulties (beta=-0.42, p<0.0005). Number of healthcare contacts over the 6 months ranged from 1 to 29, and was independently predicted by perceived cause of pain [Incident Rate Ratio (IRR)=1.46, p=0.03], Fear Avoidance Beliefs about work (IRR=1.02, p=0.009) and back pain related social difficulties (IRR=1.16, p=0.03). To conclude, anxiety, depression, fear avoidance beliefs relating to work and back pain related stresses predict impairment in subsequent physical health-related quality of life and number of healthcare contacts. Interventions targeting these psychosocial variables in clinic patients may lead to improved quality of life and healthcare costs.
心理和社会因素已分别被证明可预测慢性下腰痛患者的预后。然而,此前很少有研究将心理和社会因素结合起来,通过对下腰痛门诊患者群体进行前瞻性研究,以确定哪些是最重要的治疗靶点。108名新转诊至骨科门诊的慢性下腰痛患者完成了人口统计学特征评估、背痛细节、焦虑和抑郁测量(医院焦虑抑郁量表,HADS)、对疼痛的恐惧信念(恐惧回避信念问卷)、社会压力(生活事件和困难量表)以及健康相关生活质量的身体方面[SF-36身体成分总结评分量表(PCS)]。六个月后,受试者完成了SF-36 PCS,并记录了随访期间的医疗接触次数。在6个月随访时,SF-36 PCS的独立预测因素为疼痛持续时间[标准化回归系数(β)=-0.18,p=0.04]、HADS评分(β)=-0.27,p=0.003]以及与背痛相关的社会困难(β=-0.42,p<0.0005)。6个月内的医疗接触次数从1次到29次不等,其独立预测因素为疼痛的感知原因[发病率比值(IRR)=1.46,p=0.03]、对工作的恐惧回避信念(IRR=1.02,p=0.009)以及与背痛相关的社会困难(IRR=1.16,p=0.03)。总之,焦虑、抑郁、与工作相关的恐惧回避信念以及与背痛相关的压力可预测随后与身体健康相关的生活质量受损情况以及医疗接触次数。针对门诊患者这些心理社会变量的干预措施可能会改善生活质量并降低医疗成本。