裂孔隔膜连接复合体与细胞骨架的调控
Slit diaphragm junctional complex and regulation of the cytoskeleton.
作者信息
Garg Puneet, Verma Rakesh, Holzman Lawrence B
机构信息
Division of Nephrology, University of Michigan Medical School, Ann Arbor, MI 48109-0676, USA.
出版信息
Nephron Exp Nephrol. 2007;106(2):e67-72. doi: 10.1159/000101795. Epub 2007 Jun 6.
PMID:17570942
Abstract
In recent years, identification of proteins found at the slit diaphragm has greatly improved our understanding of the molecular mechanisms responsible for forming and maintaining the glomerular filtration barrier. This review examines the function of proteins identified at the podocyte intercellular junction in coordinating podocyte intercellular junction dynamics or cytoskeletal dynamics.
摘要
近年来，对裂孔隔膜处蛋白质的鉴定极大地增进了我们对形成和维持肾小球滤过屏障的分子机制的理解。本综述探讨了在足细胞细胞间连接处鉴定出的蛋白质在协调足细胞细胞间连接动态或细胞骨架动态方面的功能。
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