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舌痛:灼口综合征与念珠菌相关病变

Tongue pain: burning mouth syndrome vs Candida- associated lesion.

作者信息

Terai H, Shimahara M

机构信息

Department of Oral Surgery, Osaka Medical College, Osaka, Japan.

出版信息

Oral Dis. 2007 Jul;13(4):440-2. doi: 10.1111/j.1601-0825.2006.01325.x.

Abstract

OBJECTIVE

We investigated patients with tongue pain to examine whether the differential diagnosis of burning mouth syndrome and Candida-associated lesion was possible.

PATIENTS AND METHODS

Sixty patients with tongue pain were divided into three groups according to the intensity of pain at rest and that when eating using the visual analogue scale: Group A: Functional pain group. Group B: Non-functional pain group. Group C: Mixed pain group. Antifungal treatment was scheduled for patients suspected clinically, mycologically or cytologically as having candidal infection.

RESULTS

The results of the culture test and direct examination indicated that group A was different from others by its high positivity for Candida, a good response to the antifungal treatment was obtained. On the other hand, antifungal treatment was not useful in group B, and the low possibility of Candida infection in the direct examination supported the result in this group. In group C, the positivity of Candida and the effect of the antifungal treatment were between groups A and B.

CONCLUSION

These results may suggest that tongue pain in group A is Candida-associated, that in group B is burning mouth syndrome-induced and that of group C is mixed conditions.

摘要

目的

我们对舌痛患者进行调查,以检验是否有可能鉴别诊断灼口综合征和念珠菌相关病变。

患者与方法

60例舌痛患者根据静息时和进食时的疼痛强度,采用视觉模拟评分法分为三组:A组:功能性疼痛组。B组:非功能性疼痛组。C组:混合性疼痛组。对临床、真菌学或细胞学怀疑有念珠菌感染的患者安排抗真菌治疗。

结果

培养试验和直接检查结果表明,A组念珠菌阳性率高,与其他组不同,抗真菌治疗取得了良好效果。另一方面,抗真菌治疗对B组无效,直接检查中念珠菌感染可能性低支持了该组结果。C组中,念珠菌阳性率和抗真菌治疗效果介于A组和B组之间。

结论

这些结果可能表明,A组舌痛与念珠菌有关,B组为灼口综合征所致,C组为混合情况。

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