Vassallo Jessica L, Proctor-Weber Zoë, Lebowitz Brian K, Curtiss Glenn, Vanderploeg Rodney D
Department of Mental Health and Behavioral Sciences, James A. Haley VAMC. Tampa, FL 33612, USA.
Brain Inj. 2007 Jun;21(6):567-73. doi: 10.1080/02699050701426832.
To examine the risk of sustaining a traumatic brain injury (TBI) associated with prior psychiatric conditions beyond that of fixed demographic variables.
Retrospective cohort study of non-referred community-dwelling male US veterans.
Two-hundred and seventy-one individuals who sustained a TBI with altered consciousness were compared with 630 controls without a history of head injury, selected from a larger sample of 3766.
Hierarchical logistic regression analyses were used to model odds ratios and 95% confidence intervals for the unique association between pre-existing psychiatric disorders and the likelihood of incurring a TBI while adjusting for demographic characteristics and other known predictor variables. Mood (odds ratio 2.48, 95% confidence interval 1.23-5.01), anxiety (OR 1.64, 95% CI 1.01-2.68) and conduct disorders (OR 1.66, 95% CI 1.16-2.38) increased the risk of head injury.
The pre-existence of psychiatric illness, particularly depression, anxiety and conduct disorder, increased the future risk of incurring a TBI. The implementation of early identification and treatment of psychiatric conditions may potentially lower risk and reduce yearly incidence rates of TBI.
研究除固定人口统计学变量外，既往精神疾病与创伤性脑损伤（TBI）发生风险之间的关系。
对未被转诊的美国社区居住男性退伍军人进行回顾性队列研究。
从3766人的较大样本中选取271名意识改变的TBI患者与630名无头部损伤史的对照进行比较。
采用分层逻辑回归分析对既往精神疾病与发生TBI可能性之间的独特关联进行建模，并在调整人口统计学特征和其他已知预测变量的同时计算比值比和95%置信区间。情绪障碍（比值比2.48，95%置信区间1.23 - 5.01）、焦虑症（比值比1.64，95%置信区间1.01 - 2.68）和品行障碍（比值比1.66，95%置信区间1.16 - 2.38）会增加头部受伤风险。
精神疾病，尤其是抑郁症、焦虑症和品行障碍的既往病史会增加未来发生TBI的风险。实施精神疾病的早期识别和治疗可能会潜在降低风险并减少TBI的年发病率。
