一种髓鞘来源组分的个体发生学研究，该组分具有高于髓鞘的2':3'-环核苷酸3'-磷酸二酯酶活性。
Ontogenetic study of a myelin-derived fraction with 2':3'-cyclic nucleotide 3'-phosphodydrolase activity higher than that of myelin.
作者信息
Waehneldt T V
出版信息
Biochem J. 1975 Nov;151(2):435-7. doi: 10.1042/bj1510435.
Abstract
A membrane fraction (SN 4), prepared from developing and mature rat forebrain by hypo-osmotic treatment of microsome (microsomal-fraction)-free myelin, appears to be closely related to the myelin-like fraction. Fraction SN 4 shows 2':3'-cyclic nucleotide 3'-phosphohydrolase activity higher than that of the parent myelin. Electrophoresis reveals a multitude of bands with the Wolfgram protein as the main component.
摘要
通过对无微粒体（微粒体组分）髓磷脂进行低渗处理，从发育中和成熟大鼠前脑制备的膜组分（SN 4）似乎与类髓磷脂组分密切相关。组分SN 4显示出比其母体髓磷脂更高的2':3'-环核苷酸3'-磷酸水解酶活性。电泳显示出众多条带，其中沃尔夫格拉姆蛋白为主要成分。
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